All denture patients have experienced it: that day when you realize your denture is loose. There are a number of reasons your denture may start to fit poorly. Sometimes, uneven or excessive tooth wear causes your denture to tip or rock. Certain health conditions can also affect how your denture fits, such as weight loss of more than 7 pounds, sudden or new illness, cancer treatments, and various medications. However, there is one factor affecting all denture wearers that you may not have considered – bone loss.